Resolving degeneracy in diffusion MRI biophysical model parameter estimation using double diffusion encoding

Published in Magnetic Resonance in Medicine, 2019

Recommended citation: Coelho et al. Resolving degeneracy in diffusion MRI biophysical model parameter estimation using double diffusion encoding. Magn Reson Med. 2019; 82: 395– 410. http://santiagocoelho.github.io/files/paper2.pdf

This paper shows that incorporating double diffusion encoding (DDE) measurements help resolve the degeneracy in the parameter estimation for the Standard Model of diffusion in white matter for a Watson fiber distribution function (ODF). This is also the case for an arbitrary ODF, as was later proved.

A pdf of the paper can be downloaded here

Recommended citation: Coelho, S, Pozo, JM, Jespersen, SN, Jones, DK, Frangi, AF. Resolving degeneracy in diffusion MRI biophysical model parameter estimation using double diffusion encoding. Magn Reson Med. 2019; 82: 395– 410.